Caution is advised when consuming alcohol with Mabthera 500. Please consult your doctor.
CONSULT YOUR DOCTOR
Mabthera 500 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Mabthera 500 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CONSULT YOUR DOCTOR
It is not known whether Mabthera 500 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
SAFE IF PRESCRIBED
Mabthera 500 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Mabthera 500 may not be needed in these patients. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Mabthera 500 in patients with liver disease. Please consult your doctor.
Use of Mabthera 500 is not recommended in patients with the active liver disease or those who had viral hepatitis as it can reactivate the infection.
Medicine Overview of Mabthera 500mg/10ml Injection
Introduction
Mabthera 500 is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis and microscopic polyangiitis.
Mabthera 500 is given as an injection under the su ... Show more
Uses of Mabthera 500
Non-Hodgkin lymphoma (NHL)
Rheumatoid arthritis
Blood cancer (Chronic lymphocytic leukemia)
Granulomatosis with polyangiitis
Microscopic polyangiitis
Side effects of Mabthera 500
Common
Headache
Weakness
Edema (swelling)
Infection
Hair loss
Itching
Chills
Febrile neutropenia
Decreased white blood cell count (neutrophils)
Infusion reaction
Increased risk of infection
Decreased blood cells (red cells, white cells, and platelets)
How to use Mabthera 500
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Mabthera 500 works
Mabthera 500 is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.
What if you forget to take Mabthera 500?
If you miss a dose of Mabthera 500, please consult your doctor.
Quick Tips
It is given as a drip (intravenous infusion) by your doctor or nurse.
You may be given some painkillers, antihistamine and possibly steroids before the drip to help prevent infusion reaction.
Your doctor may get blood tests done to check for hepatitis B before treatment and to monitor your blood cells during treatment with this me ... Show more
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Inform your doctor if you have any heart rhythm problems, if you are having surgery or if you plan to get any vaccinations.
Brief Description
Indication
Non-Hodgkin's lymphoma; follicular lymphoma
Administration
Reconstitution: Dilute the appropriate dose w/ sodium chloride 0.9% or glucose 5% to a final concentration of between 1 and 4 mg/mL.
IV Administrat ... Show more
Adult Dose
Intravenous
Non-Hodgkin Lymphoma
Recommended dose for NHL
375 mg/m² IV infusion according to the following schedules
Relapsed or refractory low ... Show more
Child Dose
Safety and efficacy not established
Contraindication
Lactation. Type I hypersensitivity or anaphylactic reactions to murine proteins or component of the formulation.
Mode of Action
Rituximab is a chimeric monoclonal antibody to CD20 antigen which regulates cell cycle initiation. It binds to the antigen on the cell surface, activa ... Show more
Precaution
Extensive tumor burden, pulmonary tumor infiltration or pulmonary insufficiency; history of cardiac disease; effective contraception during and up to ... Show more
Side Effect
>10%
NHL
Angioedema (11%), hypotension (10%), Asthenia (26%), chills (33%), dizziness (10%), fever (53%), headache (19%)
Pruritus (14%), rash (15%) ... Show more
Interaction
Increased risk of renal toxicity w/ cisplatin.
Potentially Fatal: May decrease the efficacy of vaccines and increase the risk of infections in pati ... Show more
ফার্মেসীর জন্য পাইকারি দামে ঔষধ কিনতে রেজিস্টেশন করুন
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.