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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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Fliban 100

Tablet - (100mg)
arogga-brand
Square Pharmaceuticals PLC.
Generic: Flibanserin
৳ 454.50
৳ 500
9% OFF

Medicine Overview of Fliban 100mg Tablet

বাংলা
English
Indication
Indicated for premenopausal women with acquired, generalized, hypoactive sexual desire disorder (HSDD), as characterized by low sexual desire that causes marked distress or interpersonal difficulty and is not caused by a coexisting medical or psychiatric condition, problems within the relationship, or the effects of a medication or other drug substance,
Adult Dose
Hypoactive Sexual Desire Disorder Indicated for premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD) as characterized by low sexual desire that causes marked distress or interpersonal difficulty and is not caused by a coexisting medical or psychiatric condition, problems within the relationship, or the effects of a medication or other drug substance 100 mg PO once daily at bedtime Dosed at bedtime because administration during waking hours increases risks of hypotension, syncope, accidental injury, and CNS depression Discontinued after 8 weeks if no improvement
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Contraindication
Use with alcohol Co-administration with moderate or strong CYP3A4 inhibitors Any degree of hepatic impairment
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Mode of Action
Postsynaptic serotonin-1A (5HT-1A) receptor agonist and 5HT-2A receptor antagonist; also elicits moderate antagonist activities at the 5-HT2B, 5-HT2C, and dopamine D4 receptors The mechanism of action HSDD is not known; may work by restoring prefrontal cortex control over the brain's motivation/rewards structures, enabling sexual desire to manifest; this may occur by increasing dopamine and norepinephrine while transiently decreasing serotonin in the brain's prefrontal cortex, which may be accomplished by reduced glutamate transmission
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Precaution
Coadministration with alcohol increases the risk of severe hypotension and syncope (also see Contraindications and Black Box Warnings) Coadministration with moderate or strong CYP3A4 inhibitors is significantly increases flibanserin concentrations, which can lead to hypotension and syncope (also see Contraindications, Black Box Warnings, and Dosing) Concomitant use of multiple weak CYP3A4 inhibitors that may include herbal supplements (eg, ginkgo, resveratrol) or nonprescription drugs (eg, cimetidine) could also lead to clinically relevant increases in flibanserin concentrations that may increase the risk of hypotension and syncope Causes CNS depression (eg, somnolence, sedation); risk of CNS depression is increased if taken during waking...
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Side Effect
>10% Dizziness (11.4%) Somnolence (11.2%) Nausea (10.4%) 1-10% Fatigue (9.2%) Insomnia (4.9%) Dry mouth (2.4%) Anxiety (1.8%) Constipation (1.6%) Abdominal pain (1.5%) Metrorrhagia (1.4%) Rash (1.3%) Sedation (1.3%) Vertigo (1%)
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Pregnancy Category Note
Pregnancy There are no studies in pregnant women to inform whether there is a drug-associated risk in humans Animal data In animals, fetal toxicity only occurred in the presence of significant maternal toxicity, including reductions in weight gain and sedation Adverse reproductive and developmental effects consisted of decreased fetal weight, structural anomalies, and increases in fetal loss at exposures greater than 15 times exposures achieved with the recommended human dosage Lactation Unknown if distributed in human breast milk Excreted in rat milk Unknown whether flibanserin has effects on the breastfed infant or if it affects milk production Because of the...
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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
Register
0 People recently viewed this

Fliban 100

Tablet - (100mg)
arogga-brand
Square Pharmaceuticals PLC.
Generic: Flibanserin
৳ 454.50
৳ 500
9% OFF

Alternative Brands For Fliban 100

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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.