It is not known whether it is safe to consume alcohol with Darboren 40. Please consult your doctor.
CONSULT YOUR DOCTOR
Darboren 40 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Darboren 40 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
SAFE
Darboren 40 does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Darboren 40 is safe to use in patients with kidney disease. No dose adjustment of Darboren 40 is recommended.
CAUTION
Darboren 40 should be used with caution in patients with liver disease. Dose adjustment of Darboren 40 may be needed. Please consult your doctor.
Medicine Overview of Darboren 40 40mcg/.4ml Injection
Introduction
Darboren 40 is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.
Darboren 40 is a medicine that needs to be used with utmost ... Show more
Uses of Darboren 40
Anemia due to chronic kidney disease
Anemia due to cancer chemotherapy
Side effects of Darboren 40
Common
High blood pressure
Hypersensitivity
How to use Darboren 40
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Darboren 40 works
Darboren 40 is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.
What if you forget to take Darboren 40?
If you miss a dose of Darboren 40, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Darboren 40 helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
It is given as a single injection under your skin.
Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in y ... Show more
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure su ... Show more
Stop taking Darboren 40 and inform your doctor if you develop shortness of breath or skin rash.
Brief Description
Indication
Anaemia of chronic renal failure, Anaemia in chemotherapy patients
Adult Dose
Chronic Kidney Disease-Associated Anemia
CKD not on dialysis
Recommended starting dose: 0.45 mcg/kg IV/SC q4weeks
Consider initiating ESA treat ... Show more
Child Dose
Chronic Kidney Disease-Associated Anemia
Initiate treatment when the hemoglobin level is <10 g/dL
If the hemoglobin level approaches or exceeds 12 g ... Show more
Renal Dose
Chronic Kidney Disease-Associated Anemia
CKD not on dialysis
Recommended starting dose: 0.45 mcg/kg IV/SC q4weeks
Consider initiating ESA treat ... Show more
Contraindication
Hypersensitivity, uncontrolled hypertension.
Mode of Action
Darbepoetin alfa is a biosynthetic form of erythropoietin. Recombinant human erythropoietin with sialic acid additions to enhance stability; stimulate ... Show more
Precaution
Hypertension; history of seizures; hepatic impairment; sickle cell anaemia; sudden stabing migraine-like pain (warning sign of hypotensive crisis); ex ... Show more
Side Effect
>10%
Cancer patients
Fatigue (33%),Diarrhea (22%),Edema (21%),Fever (19%),Dizziness (14%),Arthralgia (13%),Headache (12%),Death (10%)
Chronic ren ... Show more
Pregnancy Category Note
Pregnancy
Limited available data on pregnant women are insufficient to determine a drug-associated risk of major birth defects or miscarriage; in ani ... Show more
Interaction
Antagonism of hypotensive effect and increased risk of hyperkalemia with ACE inhibitors and angiotensin II receptor antagonists. Ethanol.
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.