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Laparen 25 250mg Tablet
Laparen 25 250mg Tablet
Out of stock
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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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Laparen 25

Tablet - (250mg)

0.0/5

(0) Ratings

arogga-brand
Renata Limited
Generic: Lapatinib
Out of Stock
Currently unavailable, please request or choose another variant.
2850.00
৳ 3000
5% OFF
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Laparen 25. Please consult your doctor.
CONSULT YOUR DOCTOR
Laparen 25 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
UNSAFE
Laparen 25 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
UNSAFE
Laparen 25 may cause side effects which could affect your ability to drive.
CAUTION
Laparen 25 should be used with caution in patients with severe kidney disease. Dose adjustment of Laparen 25 may be needed. Please consult your doctor. Limited information is available on the use of Laparen 25 in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
CAUTION
Laparen 25 should be used with caution in patients with liver disease. Dose adjustment of Laparen 25 may be needed. Please consult your doctor. Limited information is available on the use of this medicine in patients with the severe liver disease.

Medicine Overview of Laparen 25 250mg Tablet

Introduction
Laparen 25 is used in the treatment of breast cancer. It shows its working by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced stage of breast cancer. Laparen 25 should be taken on an empty stomach or should be taken one hour before or 2 hour after meal. You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your need and response to treatment. You should take it exactly as your doctor has advised....
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Uses of Laparen 25
  • Breast cancer
Side effects of Laparen 25
Common
  • Abdominal pain
  • Back pain
  • Breathing problems
  • Constipation
  • Cough
  • Diarrhea
  • Fatigue
  • Headache
  • Hot flashes
  • Increased bilirubin in the blood
  • Insomnia (difficulty in sleeping)
  • Joint pain
  • Liver damage
  • Loss of appetite
  • Mucosal inflammation
  • Nausea
  • Pain in extremity
  • Rash
  • Stomatitis (Inflammation of the mouth)
  • Vomiting
  • Weakness
  • Weight gain
How to use Laparen 25
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Laparen 25 is to be taken empty stomach.
How Laparen 25 works
Laparen 25 is an anti-cancer medication. This works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which is responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways.
Quick Tips
  • It should be taken 1 hour before or after the meal, preferably at the same time every day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
  • It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
Brief Description
Indication
Breast cancer
Administration
Should be taken on an empty stomach. Take at least 1 hr before or 1 hr after a meal. Do not eat/drink grapefruit products.
Adult Dose
Oral Breast Cancer HER2-overexpressing metastatic breast cancer Indicated in combination with capecitabine for treatment of patients with advanced or metastatic breast cancer whose tumors overexpress HER2 and who have received prior therapy including an anthracycline, a taxane, and trastuzumab 1250 mg PO qDay on Days 1-21 continuously in combination with capecitabine (2000 mg/m²/day PO divided q12hr) on Days 1-14 in a repeating 21-day cycle Hormone-positive & HER2-positive advanced breast cancer Indicated in combination therapy with letrozole for treatment of postmenopausal women with hormone receptor-positive and HER2-positive breast cancer for whom hormonal therapy is indicated 1500 mg PO qDay administered continuously...
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Child Dose
Safety and efficacy not established
Contraindication
Hypersensitivity to lapatinib ditosylate
Mode of Action
Kinase inhibitor, blocks EGF-receptor HER2 kinase; tyrosing kinase inhibition possibly blocks angiogenesis and cellular proliferation.
Precaution
Evaluate left ventricular ejection fraction (LVEF) prior to treatment. Moderate or severe hepatic impairment. Patients who have or may develop QTc prolongation, including those w/ hypokalaemia or hypomagnesemia. Monitor liver function & pulmonary symptoms indicative of interstitial lung disease/pneumonitis. Pregnancy & lactation. Lactation: Do not nurse
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Side Effect
>10% (lapatinib+capecitabine) Diarrhea (65%),Anemia (56%),Hand-foot synd (53%),Increased LFTs (37-49%),Nausea (44%),Rash (28%),Vomiting (26%),Pain (23%),Neutropenia (22%),Thrombocytopenia (18%),Mucositis (15%),Stomatitis (14%),Dyspnea (12%),Dyspepsia (11%),Insomnia (10%) 1-10% Insomnia
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Interaction
Increased conc w/ CYP3A4 inhibitors (eg ketoconazole, itraconazole or grapefruit juice), midazolam, irinotecan & digoxin. Decreased conc w/ CYP3A4 inducers (eg rifampin, carbamazepine, phenytoin) & proton-pump inhibitors (eg esomeprazole). Altered pharmacokinetics w/ P-glycoprotein, breast cancer resistance protein (BCRP) inhibitors & inducers, topotecan & rosuvastation. Increased incidence & severity of adverse events w/ paclitaxel & docetaxel. CYP3A4 or CYP2C8 substrates.
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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
Register
0 People recently viewed this

Laparen 25

Tablet - (250mg)

0.0/5

(0) Ratings

arogga-brand
Renata Limited
Generic: Lapatinib
Out of Stock
Currently unavailable, please request or choose another variant.
2850.00
৳ 3000
5% OFF
Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.