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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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Ertoxa 5

Tablet - (5mg)

0.0/5

(0) Ratings

arogga-brand
Ziska Pharmaceuticals Ltd.
Generic: Ertugliflozin
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Medicine Overview of Ertoxa 5mg Tablet

বাংলা
English
Indication
Type 2 Diabetes Mellitus
Administration
Take in the morning qDay, with or without food
Adult Dose
Type 2 Diabetes Mellitus Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus Recommended starting dose is 5 mg PO qDay in the morning If starting dose tolerated and additional glycemic control is needed, increase dose to maximum of 15 mg qDay Hepatic impairment Mild-to-moderate: No dosage adjustment necessary Severe: Not recommended
Child Dose
<18 years: Safety and efficacy not established
Renal Dose
Renal impairment eGFR ?60 mL/min/1.73 m²: No dosage adjustment necessary eGFR <30 mL/min/1.73 m²: Contraindicated End-stage renal disease or dialysis: Contraindicated eGFR 30-60 mL/min/1.73 m² Initiation of ertugliflozin not recommended Continued use not recommended with persistent eGFR 30-60 mL/min/1.73 m²
Contraindication
Hypersensitivity Severe renal impairment, end-stage renal disease, or dialysis
Mode of Action
Selective sodium-glucose transporter-2 (SGLT2) inhibitor SGLT-2 inhibition lowers the renal glucose threshold (ie, the plasma glucose concentration, which exceeds the maximum glucose reabsorption capacity of the kidney); lowering the renal glucose threshold results in increased urinary glucose excretion
Precaution
Causes intravascular volume contraction; symptomatic hypotension may occur after initiating, particularly in patients with renal impairment, with low systolic blood pressure, on diuretics, or who are elderly Ketoacidosis, a serious life-threatening condition requiring urgent hospitalization, has been reported; before initiating, consider factors that may predispose patient to ketoacidosis, including pancreatic insulin deficiency from any cause, caloric restriction, and alcohol abuse; monitor for ketoacidosis and temporarily discontinue in clinical situations known to predispose to ketoacidosis (eg, prolonged fasting owing to acute illness or surgery) Renal impairment may occur owing to intravascular volume contraction; before initiating, consider factors that may predispose patients...
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Side Effect
>10% Female genital mycotic infections (9.1-12.2%) 1-10% Volume depletion adverse effects (1.9-4.4%) Male genital mycotic infections (3.7-4.2%) Urinary tract infections (4-4.1%) Headache (2.9-3.5%) Vaginal pruritus (2.4-2.8%) Increased urination (2.4-2.7%) Nasopharyngitis (2-2.5%) Back pain (1.7-2.5%) Renal adverse effects (1.3-2.5%) Weight decreased (1.2-2.4%) Thirst (1.4-2.7%)
Pregnancy Category Note
Pregnancy Based on animal data showing adverse renal effects, not recommended during the second and third trimesters of pregnancy Data are limited in pregnant women and are not sufficient to determine a drug-associated risk of adverse developmental outcomes; there are risks to the mother and fetus associated with poorly controlled diabetes in pregnancy Animal data In animal studies, adverse renal changes were observed in rats when ertugliflozin was administered during a period of renal development corresponding to the late second and third trimesters of human pregnancy; doses ~13 times the maximum clinical dose caused renal pelvic and tubule dilatations and...
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Interaction
Hypoglycemia risk increased with insulin and insulin secretagogues (eg, sulfonylureas); a lower dose of insulin or insulin secretagogue may be required Monitoring glycemic control with urine glucose tests is not recommended in patients taking SGLT2 inhibitors, as SGLT2 inhibitors, increase urinary glucose excretion and lead to positive urine glucose tests; use alternative methods to monitor glycemic control
ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
Register
0 People recently viewed this

Ertoxa 5

Tablet - (5mg)

0.0/5

(0) Ratings

arogga-brand
Ziska Pharmaceuticals Ltd.
Generic: Ertugliflozin
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Additional Offers
Cashback
৳100
For purchasing above ৳5000+
Cashback
৳80
For purchasing above ৳4000+
Cashback
৳60
For purchasing above ৳3000+
Cashback
৳40
For purchasing above ৳2000+
Cashback
৳20
For purchasing above ৳1000+
Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.