It is not known whether it is safe to consume alcohol with R-Pag 12.5. Please consult your doctor.
CONSULT YOUR DOCTOR
R-Pag 12.5 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
R-Pag 12.5 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
R-Pag 12.5 may cause side effects which could affect your ability to drive.
R-Pag 12.5 can make you dizzy and have other side effects that make you less alert. This may affect your driving ability.
SAFE IF PRESCRIBED
R-Pag 12.5 is safe to use in patients with kidney disease. No dose adjustment of R-Pag 12.5 is recommended.
However, inform your doctor if you have a kidney disease. Regular monitoring of kidney function tests may is advisable while you are taking this medicine.
CAUTION
R-Pag 12.5 should be used with caution in patients with liver disease. Dose adjustment of R-Pag 12.5 may be needed. Please consult your doctor.
Medicine Overview of R-Pag 12.5 25mg Tablet
Introduction
R-Pag 12.5 is used to treat low platelet count due to chronic immune (idiopathic) thrombocytopenic purpura (ITP) or chronic hepatitis C virus (HCV) infection. It is also used to treat severe aplastic anemia.
R-Pag 12.5 is a thrombopoietin agonist. I ... Show more
Uses of R-Pag 12.5
Low platelet count due to ITP or HCV infection
Side effects of R-Pag 12.5
Common
Nausea
Diarrhea
Upper respiratory tract infection
Vomiting
Increased liver enzymes
Muscle pain
Urinary tract infection
How to use R-Pag 12.5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. R-Pag 12.5 is to be taken empty stomach.
How R-Pag 12.5 works
R-Pag 12.5 is a thrombopoietin agonist. It works by stimulating the formation of new platelets in the blood. Platelets help to reduce or prevent bleeding.
What if you forget to take R-Pag 12.5?
If you miss a dose of R-Pag 12.5, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
Take R-Pag 12.5 on an empty stomach, either 1 hour before or 2 hours after meals.
Take R-Pag 12.5 at least 2 hours before or 4 hours after eating dairy products and calcium-fortified juices.
Should be taken on an empty stomach: Take at least 4 hr before or after antacids, dairy products or other Ca-containing food products or mineral suppl ... Show more
Adult Dose
Adult
Chronic ITP: Initial dose 50 mg once daily. Adjust to maintain platelet count greater than or equal to 50×109 /L ... Show more
Child Dose
Child 6 years or older
Chronic ITP: Initial dose 50 mg once daily.
Child 1 to 5 year
The initial dose is 25 mg once daily.
Adjust to maintain ... Show more
Renal Dose
Renal Impairment: No dose adjustment is necessary in ITP patients with renal impairment.
Contraindication
Eltrombopag is contraindicated in patients with severe hepatic impairment and who are hypersensitive to any of its excipients.
Mode of Action
Small-molecule thrombopoietin (TPO)-receptor agonist that interacts with human TPO receptor transmembrane domain of human TPO-receptor & initiates sig ... Show more
Precaution
Regularly monitor clinical haematology, platelet counts & serum liver test throughout therapy. Renal & hepatic impairment; hepatic disease. Thrombotic ... Show more
Side Effect
Most common adverse reactions are nausea diarrhea, upper respiratory tract infection, increased ALT, mayalgia, urinanry tract infection, fatigue, head ... Show more
Pregnancy Category Note
Pregnancy
Available data from published case reports and postmarketing experience with use in pregnant women are insufficient to assess any drug-asso ... Show more
Interaction
Increased plasma Cmax & AUC of HMG-CoA reductase inhibitors. Caution w/ methotrexate, topotecan. Increased conc w/ fluvoxamine; decreased conc w/ rifa ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.