It is unsafe to consume alcohol with Comet XR 500.
SAFE IF PRESCRIBED
Comet XR 500 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Comet XR 500 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
CAUTION
Comet XR 500 should be used with caution in patients with kidney disease. Dose adjustment of Comet XR 500 may be needed. Please consult your doctor.
Use of Comet XR 500 is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
CAUTION
Comet XR 500 should be used with caution in patients with liver disease. Dose adjustment of Comet XR 500 may be needed. Please consult your doctor.
Comet XR 500 is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Medicine Overview of Comet XR 500mg Tablet
Introduction
Comet XR 500 is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevent serious complications of diabetes. It is also used to treat menstruation related disorder known as Polycystic ovary syndrome (PCOS...
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Uses of Comet XR 500
Type 2 diabetes mellitus
Side effects of Comet XR 500
Common
Nausea
Vomiting
Taste change
Diarrhea
Abdominal pain
Loss of appetite
How to use Comet XR 500
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Comet XR 500 is to be taken with food.
How Comet XR 500 works
Comet XR 500 is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines and increasing the body's sensitivity to insulin.
What if you forget to take Comet XR 500?
If you miss a dose of Comet XR 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
You have been prescribed Comet XR 500 to control the blood sugar level and reduce the risk of diabetic complications such as heart attacks.
Chances of weight gain and low blood sugar are lesser with this medicine as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. C...
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Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Comet XR 500 ma...
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Prolonged use of Comet XR 500 may lead to vitamin B12 deficiency which may lead to anemia, causing fatigue, pale skin, shortness of breath o...
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Your doctor will monitor your blood sugar levels and kidney functions regularly while you are taking this medication.
Brief Description
Indication
Type 2 DM, Polycystic ovarian syndrome,
Administration
Should be taken with food.
Adult Dose
Oral
Type 2 diabetes mellitus
Adult: Conventional preparation: Initially, 500 mg bid or tid, or 850 mg 1-2 times daily, may increase gradually to 20...
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Child Dose
Oral
Type 2 diabetes mellitus
Child: >10 yr Initially, 500 mg 1-2 times daily or 850 mg once daily, may increase gradually to max 2000 mg daily in 2...
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Renal Dose
Renal impairment
Obtain eGFR before starting metformin
eGFR <30 mL/min/1.73 m²: Contraindicated
eGFR 30-45 mL/min/1.73 m²: Not recommended to initi...
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Contraindication
Acute or chronic metabolic acidosis with or without coma (including diabetic ketoacidosis). Renal failure, severe renal or hepatic impairment, acute c...
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Mode of Action
Metformin is a biguanide w/ antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It decreases hepatic glucose production b...
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Precaution
Caution when used in patients with CHF especially in those with unstable or acute heart failure. Risk of lactic acid accumulation increases with the d...
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Side Effect
Anorexia, nausea, vomiting, diarrhoea, wt loss, flatulence, occasional metallic taste; weakness; hypoglycaemia; rash, malabsorption of vit B12. Chest ...
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Interaction
Additive effect w/ sulfonylureas. Thiazide diuretics, corticosteroids, phenothiazines, OC, sympathomimetics, niacin, Ca channel blockers and isoniazid...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.