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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Criptine.
SAFE IF PRESCRIBED
Criptine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
CONSULT YOUR DOCTOR
Criptine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Criptine is usually not used during breastfeeding because it suppresses lactation.
CAUTION
Criptine may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Criptine is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Criptine may not be needed in these patients. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Criptine in patients with liver disease. Please consult your doctor.
However, a cautious use of this medicine is advised in these patients.
Medicine Overview of Criptine 2.5mg Tablet
Introduction
Criptine is a dopamine agonists and prolactin inhibitors. It is used in the treatment of medical condition occurs as of high level of prolactin such as infertility, or abnormal production of breast milk. Criptine should be taken with food, but take it at the same time every day for better results. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for...
... Show moreUses of Criptine
- High levels of prolactin
- Female infertility
- Acromegaly
Side effects of Criptine
Common
- Nausea
- Vomiting
- Headache
- Dizziness
- Fatigue
How to use Criptine
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Criptine is to be taken with food.
How Criptine works
Criptine is a dopamine receptor agonist. It decreases the release of prolactin (milk hormone) in the body. Overproduction of this hormone is associated with abnormal production of breast milk as well as suppression of the sexual glands which can cause infertility. Reducing prolactin levels with Criptine can therefore improve these conditions. In acromegaly, it works by lowering the amount of growth hormone in the body.
Quick Tips
- Criptine is used to treat conditions caused by excess production of a natural hormone called prolactin such as infertility, or abnormal production of breast milk (galactorrhoea).
- It should be taken with or after food to avoid side effects such as nausea or indigestion.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Use caution while driving or doing anything that requires concentration as Criptine can cause dizziness and sleepiness.
- Do not take Criptine if you are breastfeeding.
- Monitoring of blood pressure may be advised regularly during treatment with Criptine.
Brief Description
Indication
Parkinson's disease, Galactorrhoea, Hypogonadism, Infertility, acromegaly, Lactation suppression, benign breast and menstrual disorders, Amenorrhea, hyperprolactinaemia
.
Administration
Should be taken with food.
Adult Dose
Adult: PO Parkinson's disease As adjunct to levodopa: 1st wk: 1-1.25 mg at night, 2nd wk: 2-2.5 mg at night; 3rd wk: 2.5 mg twice daily; 4th wk: 2.5 mg 3 times/day, then increase as needed. Maintenance: 10-40 mg/day. Hyperprolactinemia Initial: 1.25-2.5 mg PO qDay May increase by 2.5 mg/day q2-7Days Usual therapeutic dosage 5-7.5 mg/day, ranges from 2.5-15 mg/day Up to 30 mg/day has been used in some patients with amenorrhea &/or galactorrhea Acromegaly (Parlodel) 1.25-2.5 mg PO qHS for 3 days May increase by 1.25-2.5 mg/day at q3-7Days Not to exceed 100 mg/day Adjunct to surgery and radiotherapy...
... Show moreChild Dose
Hyperprolactinemia
11-15 years: 1.25-2.5 mg PO qDay (initially)
Maintenance: 2.5-10 mg/day
Contraindication
Breast carcinoma, hypersensitivity to ergot alkaloids, uncontrolled hypertension, severe ischaemic heart disease. Pregnancy and lactation.
Mode of Action
Bromocriptine is a dopamine D2 and D3-agonist which works by activating postsynaptic dopamine receptors in the tuberoinfundibular and nigrostriatal pathways. It also inhibits the secretion of prolactin from the anterior pituitary and is used in the treatment of prolactinoma and in endocrinological disorders.
Precaution
Increased risk of conception, patients with peptic ulcer, diabetes, diabetic retinopathy, impaired hepatic or renal function, pleuropulmonary signs and symptoms, history of psychosis, CV disease, dementia or concurrent antihypertensive therapy, ability to drive vehicles or operating machinery may be impaired.
Lactation: should not be used during lactation
Side Effect
>10%
Nausea (49%),Hypotension (30%),Headache (19%),Dizziness (17%)
1-10%
Abdominal cramps,Anorexia,Constipation,Dyspepsia,Dysphagia,Epigastric pain,GI hemorrhage,Vomiting,Drowsiness,Fatigue,Faintness,Hallucinations Visual,Insomnia,Lightheadedness,Nighmares,Paranoia,Psychosis,Seizure,Vertigo,Arrhythmias,Bradycardia,Hypertension,MI,Mottled skin,Orthostasis,Vasospasm,Palpitations,Pericardial effusions,Raynaud's syndrome exacertabtion,Syncope,Blepharospasm,BUN increased,Burning discomfort of the eye,Diplopia,Facial pallor,Leg cramps,Nasal congestion,Rash,Urticaria
Pregnancy Category Note
Pregnancy Safety of Bromocriptine treatment during pregnancy to the mother and fetus has not been established If pregnancy occurs during Bromocriptine administration, careful observation of these patients is mandatory Prolactin-secreting adenomas may expand and compression of optic/other cranial nerves may occur, emergency pituitary surgery becoming necessary; in most cases, the compression resolves following delivery Reinitiation of Bromocriptine treatment has been reported to produce improvement in the visual fields of patients in whom nerve compression has occurred during pregnancy In patients being treated for hyperprolactinemia, Bromocriptine should be withdrawn when pregnancy is diagnosed Acromegaly, prolactinoma, or Parkinson disease Patients who subsequently...
... Show moreInteraction
Bioavailability increased if given along with erythromycin. Alcohol reduces tolerance to bromocriptine and vice-versa. Effects of antihypertensives may be potentiated. Avoid concurrent psychotropics.
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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.
