Caution is advised when consuming alcohol with Dotin 1 Please consult your doctor.

During pregnancy, Dotin 1 should only be treated if the therapeutic benefits are judged to outweigh the risks.

This drug is excreted in breast milk. Consult your doctor before breastfeeding.

It is not known whether Dotin 1 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Consider treatment with other agents. Since this drug acts in the renal proximal tubule, its efficacy may be reduced depending on the degree of renal dysfunction. In particular, administration of this drug should be avoided in patients with oliguria ...

Careful follow-up should be performed. Serious liver damage has been observed with other uricosuric agents.