Nepitan is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Nepitan is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Nepitan may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Nepitan should be used with caution in patients with severe kidney disease. Dose adjustment of Nepitan may be needed. Please consult your doctor.
Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.
CAUTION
Nepitan should be used with caution in patients with liver disease. Dose adjustment of Nepitan may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate liver disease.
Medicine Overview of Nepitan 24mg+26mg Tablet
Introduction
Nepitan is a combination medicine used to treat heart failure. It reduces the risk of hospitalization and death due to long-lasting (chronic) heart failure.
Nepitan can be taken with or without food but is best taken at the same time(s) each day. Sw ... Show more
Uses of Nepitan
Heart failure
Side effects of Nepitan
Common
Cough
Dizziness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Altered levels of potassium in blood
Decreased red blood cell count
Decreased blood pressure
Hypoglycemia (low blood glucose level)
Diarrhea
Fainting
Headache
Nausea
Stomach pain
Vertigo
Weakness
How to use Nepitan
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nepitan may be taken with or without food, but it is better to take it at a fixed time.
How Nepitan works
Nepitan is a combination of two medicines: Sacubitril and Valsartan which belong to a class of angiotensin receptor neprilysin inhibitor (ARNI). This combination treats heart failure by relaxing the blood vessels and making it easier for your heart t ... Show more
Quick Tips
You have been prescribed Nepitan for the treatment of of long-lasting (chronic) heart failure.
You should continue to stay active (light walking, stretching) and eat a healthy, low sodium diet along with taking this medication.
To reduce the chances of feeling dizzy, rise slowly if you have been sitting or lying down.
It may cause the level of potassium in your blood to go up. Avoid taking potassium supplements and potassium-rich foods such as banana and b ... Show more
Inform your doctor if you have a history of liver or kidney diseases.
Do not take Nepitan if you are pregnant or breastfeeding.
Brief Description
Indication
Heart Failure,
Administration
May take with or without food
Adult Dose
Heart Failure
Indicated to reduce the risk of cardiovascular death and hospitalization for heart failure (HF) in patients with chronic heart failure ... Show more
Renal Dose
Renal impairment
Mild-to-moderate (eGFR ?30 mL/min/1.73 m²): No starting dose adjustment required
Severe (eGFR <30 mL/min/1.73 m²): Reduce starting ... Show more
Contraindication
Hypersensitivity to any component
History of angioedema related to previous ACE inhibitor or ARB therapy
Coadministration of neprilysin inhibitors ( ... Show more
Mode of Action
Combination is an angiotensin receptor-neprilysin inhibitor (ARNi)
Sacubitril: Neprilysin inhibitor; neprilysin is responsible for degradation of atr ... Show more
Precaution
Can cause fetal harm when administered to a pregnant woman; use of drugs that act on the renin-angiotensin system during the second and third trimeste ... Show more
Side Effect
>10%
Hypotension (18%)
Hyperkalemia (12%)
1-10%
Cough (9%)
Dizziness (6%)
Orthostasis (2.1%)
Falls (1.9%)
<1%
Angioedema, all patients (0 ... Show more
ফার্মেসীর জন্য পাইকারি দামে ঔষধ কিনতে রেজিস্টেশন করুন
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.