Ligazid MX is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Ligazid MX is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
CAUTION
Ligazid MX should be used with caution in patients with kidney disease. Dose adjustment of Ligazid MX may be needed. Please consult your doctor.
Use of Ligazid MX is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
CAUTION
Ligazid MX should be used with caution in patients with liver disease. Dose adjustment of Ligazid MX may be needed. Please consult your doctor.
Ligazid MX is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Medicine Overview of Ligazid MX 5mg+1000mg Tablet
Introduction
Ligazid MX is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chance of having a ... Show more
Uses of Ligazid MX
Type 2 diabetes mellitus
Side effects of Ligazid MX
Common
Diarrhea
Nausea
Vomiting
Upset stomach
Headache
Nasal congestion (stuffy nose)
Sore throat
Respiratory tract infection
Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
How to use Ligazid MX
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ligazid MX is to be taken with food.
How Ligazid MX works
Ligazid MX is a combination of two antidiabetic medicines: Metformin and Linagliptin. Metformin is an antidiabetic medication (biguanide). It works by lowering the glucose production in the liver, delaying glucose absorption from the intestines and i ... Show more
What if you forget to take Ligazid MX?
If you miss a dose of Ligazid MX, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Trajenta Duo 2.5mg/500mg Tablet should be taken with food to lower the chances of having an upset stomach.
Take it in addition to regular exercise and a healthy diet to lower the levels of blood sugar.
Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. C ... Show more
Monitor your blood sugar level regularly while you are taking this medicine.
Inform your doctor about your diabetes treatment if you are due to have any surgery under a general anaesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting or stomach pain as Trajenta Duo 2.5m ... Show more
Brief Description
Indication
Type 2 Diabetes mellitus
Administration
Should be taken with meals to reduce the gastrointestinal undesirable effects associated with metformin.
Adult Dose
Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both linagliptin ... Show more
Child Dose
<18 years: Safety and efficacy not established
Renal Dose
Renal impairment
Obtain eGFR before starting metformin
eGFR <30 mL/min/1.73 m²: Contraindicated
eGFR 30-45 mL/min/1.73 m²: Not recommended to ini ... Show more
Contraindication
Hypersensitivity. Type 1 diabetes, diabetic ketoacidosis or pre-coma, renal failure or dysfunction (CrCl <60 mL/min), hepatic insufficiency, acute alc ... Show more
Mode of Action
Linagliptin: Dipeptidyl peptidase 4 (DPP-4) inhibitor; increases and prolongs incretin hormone activity from glucagon-like peptide-1 (GLP-1) and gluco ... Show more
Precaution
Monitor for pancreatitis, hypoglycaemia, lactic acidosis, renal impairment. Intravascular administration of iodinated contrast agents. Co-administrati ... Show more
Side Effect
>10%
Hypoglycemia (with sulfonylurea) (22.9%)
1-10%
Nasopharyngitis (6.3%),Diarrhea (6.3%),Hypoglycemia (without sulfonylurea) (1.4%)
Frequenc ... Show more
Interaction
Linagliptin: Inhibits P-glycoprotein-mediated transport of digoxin (w/ low potency). Increased AUC & Cmax w/ ritonavir. Decreased steady-state AUC & C ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.