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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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Lipoxin B Injection

injection - (500000/Unit)
arogga-brand
Opsonin Pharma Limited
Generic: Polymyxin B Sulfate
৳ 363.60
৳ 400
9% OFF

Medicine Overview of Lipoxin B Injection 500000/Unit injection

বাংলা
English
Indication
Susceptible infections, Meningitis
Administration
IV/IM/IT Preparation IV: dilute 500,000 U in 300-500 mL D5W IM: reconstitute vial with 2 mL SWI , NS, or procaine HCl 1% solution Intrathecal (IT): reconstitute vial with10 mL NS; DO NOT use procaine HCl for IT IV/IM Administration IV: infuse over 60-90 min IM: give deep into upper outer quadrant of gluteal muscles
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Adult Dose
Intravenous Susceptible infections Adult: 15,000-25,000 U/kg daily by continuous IV drip or intermittent infusion 12 hrly at 60-120 min duration. Max: 2,000,000 U/day. Intramuscular Susceptible infections Adult: 25,000-30,000 U/kg daily in divided doses 4-6 hrly. Max: 2,000,000 U/day. Intrathecal Meningitis Adult: 50,000 U once daily for 3-4 days, then on alternate days for at least 2 wk after CSF cultures are negative and CSF glucose content is normal. Max: 2,000,000 U/day.
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Child Dose
Intravenous Susceptible infections Adult: 15,000-25,000 U/kg daily by continuous IV drip or intermittent infusion 12 hrly at 60-120 min duration. Max: 2,000,000 U/day. Child: <2 yr 40,000 U/kg daily in divided doses 12 hrly; ?2 yr Same as adult dose. Intramuscular Susceptible infections Child: <2 yr 40,000 U/kg daily in divided doses 6 hrly (not routinely recommended due to pain at injection sites); >2 yr Same as adult dose but not routinely recommended due to pain at injection sites. Intrathecal Meningitis Child: <2 yr 20,000 U once daily for 3-4 days or 25,000 U on alternate days, followed by the...
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Renal Dose
Renal Impairment CrCl >20 mL/minute: give 75-100% usual dose/day divided q12hr CrCl 5-20 mL/minute: give 50% usual dose/day divided q12hr CrCl <5 mL/minute: give 15% usual dose/day q12hr
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Contraindication
Hypersensitivity to polymyxins; Concurrent use w/ nephrotoxic and/or neurotoxic drugs and neuromuscular blockers.
Mode of Action
Polymyxin B binds to phospholipids, alters permeability and disrupts the bacterial cytoplasmic membrane of mostly gm-ve organisms allowing leakage of intracellular constituents by binding to membrane phospholipids.
Precaution
Oliguria, myasthenia gravis, pregnancy, renal disease Potential risk of nephrotoxicity and neurotoxicity May inhibit neuromuscular transmission Inactivated by strong acidic or alkaline solution Discontinue if diminished urine output, rise in SCr or BUN, or signs of respiratory paralysis appear Do not use IM routinely, particularly in peds, because of severe inj site pain
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Side Effect
Frequency Not Defined Anaphylactoid reactions with dyspnea and tachycardia Eosinophilia Fever Nephrotoxicity Neurotoxicity Skin exanthemata Urticaria
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Pregnancy Category Note
Pregnancy Category: B: use when benefits outweigh risks Lactation: use caution; no data
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Interaction
Potentially Fatal: Additive neurotoxic or nephrotoxic effect w/ bacitracin, streptomycin, neomycin, kanamycin, gentamicin, tobramycin, amikacin, cephaloridine, paromomycin, viomycin, colistin. Increased risk of resp paralysis w/ neuromuscular blockers (e.g. anaesthetics, muscle relaxants).
ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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0 People recently viewed this

Lipoxin B Injection

injection - (500000/Unit)
arogga-brand
Opsonin Pharma Limited
Generic: Polymyxin B Sulfate
৳ 363.60
৳ 400
9% OFF

Alternative Brands For Lipoxin B Injection

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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.