It is unsafe to consume alcohol with Glipizide.

Glipizide may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Glipizide is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Glipizide

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Glipizide should be used with caution in patients with severe kidney disease. Dose adjustment of Glipizide may be needed. Please consult your doctor. These patients can experience very low blood sugar levels with this medicine, which may take a long time to come back to normal

Glipizide should be used with caution in patients with severe liver disease. Dose adjustment of Glipizide may be needed. Please consult your doctor.