Caution is advised when consuming alcohol with Aprima 10. Please consult your doctor.
CONSULT YOUR DOCTOR
Aprima 10 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you....
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CONSULT YOUR DOCTOR
Information regarding the use of Aprima 10 during breastfeeding is not available. Please consult your doctor.
SAFE
Aprima 10 does not usually affect your ability to drive.
CAUTION
Aprima 10 should be used with caution in patients with severe kidney disease. Dose adjustment of Aprima 10 may be needed. Please consult your doctor.
SAFE IF PRESCRIBED
Aprima 10 is safe to use in patients with liver disease. No dose adjustment of Aprima 10 is recommended.
Medicine Overview of Aprima 10mg Tablet
Introduction
Aprima 10 is used in the treatment of moderate to severe plaque psoriasis which is a type of skin condition. This medicine is used when other conventional treatments cannot be used or if the patient is not responsive or intolerant to any of these tre...
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Uses of Aprima 10
Plaque psoriasis
Side effects of Aprima 10
Common
Diarrhea
Nausea
Vomiting
How to use Aprima 10
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aprima 10 may be taken with or without food, but it is better to take it at a fixed time.
How Aprima 10 works
Aprima 10 is a phosphodiesterase 4 (PDE4) inhibitors. It works by blocking the action of certain chemical messengers that are responsible for inflammation associated with psoriatic arthritis and psoriasis, and thereby reduces the signs and symptoms o...
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Quick Tips
Aprima 10 is a well-tolerated medicine. Mild stomach upset may occur early during the treatment.
Monitor your weight regularly as Aprima 10 may cause weight loss.
Your doctor will gradually increase the dose from day 1 to day 6 of treatment, after which it may be kept constant.
Tell your doctor immediately if you experience new or worsened depression, suicidal thoughts, other mood changes or unexplained weight loss.
Brief Description
Indication
Active psoriatic arthritis, moderate to severe plaque psoriasis
Administration
To reduce risk of GI symptoms associated with initial therapy, titrate to recommended dose (30 mg PO BID) according to the dosage schedules listed abo...
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Adult Dose
Active psoriatic arthritis, moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate.
To reduce risk of gastroint...
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Renal Dose
Severe renal impairment (CrCl <30 mL/min): Reduce dose to 30 mg PO qDay
Mild-to-moderate renal impairment: No dosage adjustment required
Contraindication
Known hypersensitivity to apremilast.
Mode of Action
Apremilast is an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4) specific for cyclic adenosine monophosphate (cAMP). PDE4 inhibition resul...
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Precaution
Apremilast is associated with an increase in adverse reactions of depression. Before using, evaluate patient for history of depression and/or suicidal...
Pregnancy
Available pharmacovigilance data use in pregnant women have not established a drug-associated risk of major birth defects, miscarriage or a...
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Interaction
Coadministration with strong CYP inducers (eg, rifampin, carbamazepine, phenobarbital phenytoin) may occur and result in a loss of efficacy of apremil...
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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.