Oral
Adult: 1-2 tablet daily or divided doses.
Parenteral
Adult: 1 ampoule (2 ml) given via SC, IM or IV routes daily or can be given 1 ampoule 2-3 times a week..
Contraindication
Contraindicated in patients with a known hypersensitivity to any of the ingredients. Patients receiving levodopa.
Mode of Action
Pyridoxine is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. It is essential in Hb formation and GABA synthesis within the CNS. It also aids in the release of glycogen stored in the liver and muscles.
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Precaution
Drug interaction with levodopa.
Side Effect
Generally well tolerated.
Interaction
Pyridoxine: Isoniazid, penicillamine and oral contraceptives may result in greater requirement in pyridoxine dose. Reduces the effects of levodopa, phenobarbitone, altretamine and phenytoin.
Riboflavin: Rate and extent of absorption may be affecte ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.