Gefiren is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Gefiren is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Gefiren may cause side effects which could affect your ability to drive.
Gefiren may make you feel weak. This may affect your driving ability.
CAUTION
Gefiren should be used with caution in patients with severe kidney disease. Dose adjustment of Gefiren may be needed. Please consult your doctor.
SAFE IF PRESCRIBED
Gefiren is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Gefiren may not be needed in these patients. Please consult your doctor.
Medicine Overview of Gefiren 250mg Tablet
Introduction
Gefiren is used in the treatment of non-small cell lung cancer. It is used in patients in which it has spread to other parts of the body, who have abnormal epidermal growth factor receptor (EGFR) genes, and who have not had previous treatment for can...
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Uses of Gefiren
Non-small cell lung cancer
Side effects of Gefiren
Common
Diarrhea
Dry skin
Loss of appetite
Nausea
Rash
Stomatitis (Inflammation of the mouth)
Vomiting
Weakness
How to use Gefiren
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gefiren may be taken with or without food, but it is better to take it at a fixed time.
How Gefiren works
Gefiren is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
What if you forget to take Gefiren?
If you miss a dose of Gefiren, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
Gefiren helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
Take it with or without food, preferably at the same time each day.
Do not take antacids (to reduce the acid level of your stomach) 2 hours before or 1 hour after taking this medicine.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of brea...
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Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
Brief Description
Indication
Non-small Cell Lung Cancer
Administration
Film-coated tab: May be taken with or without food. May also be dispersed in ½ glass of plain, non-carbonated water. No other liqd should be used. Dro...
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Adult Dose
Oral
Locally advanced or metastatic non-small cell lung carcinoma
Adult: 250 mg once daily until disease progression or unacceptable toxicity
Contraindication
Hypersensitivity. Lactation.
Mode of Action
Gefitinib is a synthetic anilinoquinazoline which inhibits the intracellular phosphorylation of numerous tyrosine kinases associated w/ transmembrane ...
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Precaution
Patients w/ concurrent idiopathic pulmonary fibrosis, acute onset or worsening pulmonary or eye symptoms. Renal and hepatic impairment. Pregnancy. Mon...
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Side Effect
>10%
Skin reactions, all grades (47%),Diarrhea, all grades (29%),Decreased appetite, all grades (17%),Vomiting, all grades (14%),Increased ALT, all g...
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Interaction
Concomitant use w/ CYP3A4 inducers (e.g. rifampicin, phenytoin, carbamazepine, barbiturates) may reduce serum gefitinib levels. Plasma concentrations ...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.